Oscillations Go the Distance: Low-Frequency Human Hippocampal Oscillations Code Spatial Distance in the Absence of Sensory Cues during Teleportation
نویسندگان
چکیده
Low-frequency (delta/theta band) hippocampal neural oscillations play prominent roles in computational models of spatial navigation, but their exact function remains unknown. Some theories propose they are primarily generated in response to sensorimotor processing, while others suggest a role in memory-related processing. We directly recorded hippocampal EEG activity in patients undergoing seizure monitoring while they explored a virtual environment containing teleporters. Critically, this manipulation allowed patients to experience movement through space in the absence of visual and self-motion cues. The prevalence and duration of low-frequency hippocampal oscillations were unchanged by this manipulation, indicating that sensorimotor processing was not required to elicit them during navigation. Furthermore, the frequency-wise pattern of oscillation prevalence during teleportation contained spatial information capable of classifying the distance teleported. These results demonstrate that movement-related sensory information is not required to drive spatially informative low-frequency hippocampal oscillations during navigation and suggest a specific function in memory-related spatial updating.
منابع مشابه
Multisensory control of hippocampal spatiotemporal selectivity.
The hippocampal cognitive map is thought to be driven by distal visual cues and self-motion cues. However, other sensory cues also influence place cells. Hence, we measured rat hippocampal activity in virtual reality (VR), where only distal visual and nonvestibular self-motion cues provided spatial information, and in the real world (RW). In VR, place cells showed robust spatial selectivity; ho...
متن کاملSimulation of Single Conductors Galloping Oscillations and Estimation of their Maximum Amplitudes
Overhead transmission lines are influenced by different factors which are mostly electrical and mechanical. These factors can cause problems for lines, distortions in network and outage of line. In designing transmission lines mechanical properties are evaluated after selecting a suitable conductor and clearance with regard to electrical properties. In lines designing, an important mechanical p...
متن کاملHuman Hippocampal Theta Oscillations during Movement without Visual Cues
The hippocampus exhibits theta oscillations when animals navigate. Vass et al. (2016) discovered that theta oscillations are also present when humans are moved through a virtual environment without sensory feedback, indicating that theta oscillations have a general role in spatial cognition beyond sensorimotor processing.
متن کاملSimulation of Single Conductors Galloping Oscillations and Estimation of their Maximum Amplitudes
Overhead transmission lines are influenced by different factors which are mostly electrical and mechanical. These factors can cause problems for lines, distortions in network and outage of line. In designing transmission lines mechanical properties are evaluated after selecting a suitable conductor and clearance with regard to electrical properties. In lines designing, an important mechanical p...
متن کاملTheta-Burst Stimulation of Hippocampal Slices Induces Network-Level Calcium Oscillations and Activates Analogous Gene Transcription to Spatial Learning
Over four decades ago, it was discovered that high-frequency stimulation of the dentate gyrus induces long-term potentiation (LTP) of synaptic transmission. LTP is believed to underlie how we process and code external stimuli before converting it to salient information that we store as 'memories'. It has been shown that rats performing spatial learning tasks display theta-frequency (3-12 Hz) hi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Neuron
دوره 89 شماره
صفحات -
تاریخ انتشار 2016